We have been conducting researches on FPP on the theme of "Healthy Aging", aimed at achieving to reduce medical costs though preventive medicine.

FILE : Age-Related Diseases

• 2023

  Effects of dietary supplementation with fermented papaya on oxidative stress, symptoms, and microbiome in Parkinson's disease

  Whole-BodyAge-Related DiseasesClinical Research

• 2022

  Effectiveness of a Fermented Functional Food on Telomere Dynamics and miRNAs in Middle-Aged/Elderly Healthy Individuals: A 2-Year Randomized, Double-Blind, Controlled Clinical Trial

  Whole-BodyAge-Related DiseasesClinical Research

• 2020

  MITOCHONDRIAL AND REDOX DYSFUNCTION IN POST-MENOPAUSE AS RISK FACTOR OF NEURODEGENERATIVE DISEASE: A PILOT STUDY TESTING THE ROLE OF A VALIDATED JAPANESE FUNCTIONAL FOOD

  BrainWhole-BodyAge-Related DiseasesNeurodegenerative DiseaseClinical Research

• 2020

  Beneficial Effects of Fermented Papaya Preparation (FPP)Supplementation on Redox Balance and Aging in a Mouse Model

  Whole-BodyAge-Related DiseasesRedox BalanceBasic Research

• 2019

  Oral Administration of FPP Controls the Growth of a Murine Melanoma through the In Vivo Induction of a Natural Antioxidant Response

  SkinWhole-BodyAge-Related DiseasesCancerBasic Research

• 2018

  Effects of Fermented Papaya Preparation (FPP) on Safety Outcomes in Older Adults　- A Short Report of a Placebo-Controlled Clinical Trial

  Circulatory SystemWhole-BodyAge-Related DiseasesClinical Research

• 2017

  A 2-year Double-Blind RCT Follow-up Study with Fermented Papaya Preparation (FPP) Modulating Key Markers in Middle-Age Subjects with Clustered Neurodegenerative Disease-Risk Factors

  BrainAge-Related DiseasesNeurodegenerative DiseaseClinical Research

• 2016

  Effect of a quality-controlled fermented nutraceutical on skin aging markers: An antioxidant-control, double-blind study

  SkinAge-Related DiseasesClinical Research

• 2015

  Oxidative Stress in Patients with Alzheimer's Disease: Effect of Extracts of Fermented Papaya Powder

  BrainAge-Related DiseasesNeurodegenerative DiseaseClinical Research

• 2007

  Nutraceutical Strategy in Aging Targeting Heat Shock Protein and Inflammatory Profile through Understanding Interleukin-6 Polymorphism

  BloodWhole-BodyAge-Related DiseasesClinical Research