About FPP
Patents of FPP
What is Fermented Papaya Preparation?
・Produced in Japan with international standard certifications:
ISO9001, ISO14001, ISO22000 and FSSC22000
・Trusted by athletes worldwide -- Immun'Âge® is informed Sport certified for safe use
Energize Your Cells, Strengthen Your Immune System
FPP activates mitochondria to boost energy production & support immune defense.
Patent1"ATP Production Promoter,
Mitochondrial Activity Promoter, and Immunostimulant"
No.6401792
Mitochondria is the 'power plants' of our cells, producing ATP, energy essential for life. When mitochondrial function declines, cells lack the energy they need, which can lead to chronic inflammation such as ageing, diabetes and Alzheimer's disease.
FPP helps activate mitochondria and promote energy production. By supporting cellular vitality, FPP enhances immune function -- protecting the body against infections and recover faster.
Dickerson, R., Banerjee, J., & Roy, S. (2015). Does oral supplementation of a fermented papaya preparation correct respiratory burst function of innate immune cells in type 2 diabetes mellitus patients?. AntioxidRedox Signal. 22(4):339-345 .
Protecting the Brain from Everyday Electromagnetic Stress
FPP helps defend against digital fatigue & supports healthy cognitive function.
Patent 2 & 3"Method for Treating Electrohypersensitivity
Pharmaceutical Composition for Treating Electrohypersensitivity"
No.7026387, US10,993,980 B2
Electromagnetic hypersensitivity (EHS) is increasing common, causing headaches, fatigue, poor concentration and insomnia due to exposure to everyday digital devices such as smartphones, computers, microwaves etc...
FPP helps reduce oxidative stress, improve brain blood flow and ease inflammation associated with EHS -- supporting brain health and helping to prevent cognitive decline, dementia.
Irigaray, P., Garrel, C., & Belpomme, D. (2018). Beneficial effects of a Fermented Papaya Preparation for the treatment of electrohypersensitivity self-reporting patients: Results of a phase I-II clinical trial with special reference to cerebral pulsation measurement and oxidative stress analysis. FFHD. 8(2):122-144.
Protecting Your Cells' Timekeepers -- Stay Younger, Longer
FPP supports telomere health & promotes healthy ageing.
Patent 4 "Composition for Elongating Telomere"
No.7449588
Cells in the body divide repeatedly to maintain healthy function, and this process is regulated by structures called telomeres. Telomeres shorten with each cell division. When they reach a critical length, cells stop dividing and enter a cellular senescence -- a hallmark of aging.
FPP improves oxidative stress that promotes telomere shortening and appropriately activates the enzyme (telomerase) that maintains telomere length to slow down cellular ageing.
Logozzi, M., Raimo, R. D., & Fais, S. (2020). Beneficial effects of fermented papaya preparation (FPP®) supplementation on redox balance and aging in a mouse model. Antioxidants, 9(2), 144.
The Master Regulator of Cellular Defense
FPP activates Nrf2 to coordinate antioxidant, detoxifying & immune-supportive actions.
Patent 5 "Nuclear Nrf2 Enhancer"
No.7671550
NRF2 acts as a 'command center' that protects the body by moving into the nucleus of cells under oxidative stress and activating genes involved in antioxidant, anti-inflammatory, and detoxification functions. FPP activates Nrf2, promoting a coordinated antioxidant, anti-inflammatory, and immune-regulating response that helps protect against chronic inflammation associated with ageing.
Cervi, J., Rastmanesh, R., ... & He, F. (2024). Comparing fermented food and vitamin E on exercise-mediated Nrf2/ARE activation in middle-aged/ elderly: A randomized, double-blind clinical study. Functional Food Science, 4(11): 413-426.
The Sugar Your Body Can Use for Energy and Immune Support
FPP fuels your cells, supporting energy metabolism & immune function.
Patent 6 "Method for Treating Type 2 Diabetic Patients"
US12,324,822 B2
In diabetes, cells cannot properly use sugar--their main source of energy -- leading to reduced cellular vitality and weakened immune defenses. FPP, main component is carbohydrate, serves as a safe and effective energy source that supports cellular metabolism and enhances natural immune function through the respiratory burst.
Dickerson, R., Banerjee, J., & Roy, S. (2015). Does oral supplementation of a fermented papaya preparation correct respiratory burst function of innate immune cells in type 2 diabetes mellitus patients?. Antioxid Redox Signal. 22(4):339-345 .