From 1st to 3rd of August 1995, the Osato Research Institute supported the convening of the international workshop called "A Nutritional Approach to Aging and Disease"(The UNESCO Molecular Cytology Research Network, sponsored by Gifu Prefecture). We continue to do research on food product for anti-aging and prevention of illness in cooperation with laboratories in Japan, the U.S.A., and Europe. In 2005, the Foundation Osato Research Institute was founded to reduce medical costs in the aging society.
Senior Director of Osato Research Institute
Prof. Eliezer A. RACHMILEWITZ M.D.Rachmilewitz
Graduated Hebrew University.
Hebrew University, Hadassah Medical School, Jerusalem
Internship - Hadassah University Hospital and Rambam Hospital
1961:Received M.D. Degree
1976:Acting Head, Hematology Service, Hadassah University Hospital
1978-1980:Head, Hematology Service, Hadassah University Hospital
1981-2000:Head, Department of Hematology, Hadassah Medical Organization
April 1999-present:Head, Hematology Institute, Wolfson Medical Center
I feel honored to be the senior director of the Osato Research Institute.
I assumed the position because Mr. Hayashi is one of my longtime friends and I fully appreciate his idea to reduce medical cost in the aging society, which is the main reason why ORI was established.
I have been interested for years in congenital and acquired hemolytic anemias where oxidative stress is playing a major pathophysiological role. This is how I became involved in studying the effects of FPP (Fermented Papaya Preparation) which is a very unique food capable of adjusting oxidative stress within a living organism with a concomitant increase in antioxidant enzymes in the body such as Gluthatione (GSH).
I think that FPP can be used in a variety of disorders where oxidative stress is playing a role alone or in combination with other drugs.
I have used FPP to treat patients with thalassemia and showed amelioration of parameters of oxidative stress. (Amer J et al. "Fermented Papaya Preparation as an antioxidant in blood cells of beta thalassemic mice and patients." Phytotherapy Research. 22:820-828, 2008).
I am planning to extend the studies with FPP to other disorders such as diabetes, arteriosclerosis and neurodegenerative disorders, etc…
Director of Osato Research Institute
Dr. Pierre Mantello, Ph.D., M.D.
Biologist EC4 (European Communities Confederation of Clinical Chemistry)
CES.Bacteriology, Virology, Parasitology, Hematology, and Biochemistry
Gold Medal Graduate, Medical University of Grenoble, France
Since many centuries ago, the quest for eternal youth has been the main human preoccupation. Even though nobody has found the solution, Twentieth Century scientific progress has doubled the life span of humans and this duration is now in accordance with the one programmed in the human genome (between 100 and 120 years old). Scientific progress has also provided us new pathologies through the transformation of the environment (such as pollution, different habits, and new ways of life); but it seems useless to live to 120 if you have to endure degenerative diseases that make you lose your intellectual and physical capacities. If the Twentieth Century has given us a longer life span, then the Twenty-First Century will procure a long and healthy life for us. The best quality of life for all---thatﾕs the aim of the Osato Research Institute. F.P.P. is the fruit of all our anti-aging research.
Deputy Director of Osato Research Institute
Okuda Sachiko Ph.D.
She was graduated from Physical Chemistry Dept. of Ochanomizu Women's University (Japan), and received her MSc degree in physical chemistry from U.C. San Diego(USA) and PhD degree from University of Southampton(UK) for researches on angular distribution of photo-dissociation products, and infrared emission from molecular reactions.
She also has held important positions in organizations such as Director(Interim Board Member) of INWES(International Network of Women Engineers and Scientists), President of INWES Japan and Vice President of Japanese Academy of Facial Studies.
ORI is a very unique research institute. It is a great inspiration to me that ORI is involved in international research activity but also its involvement in charity activities such as supporting the World Foundation Aids Research and Prevention's Japan Office as well as other social activities for the local children. The sole focus of our research is "FPP" (Fermented Papaya Preparation) and famous scientists all over the world have been cooperating with our research activities as members of the ORI Scientific Board, to substantiate FPP's effect on immune adjustment with clinical data and its mechanism of involvement in our internal Redox systems. We have members of the board in different fields, in different countries, and each of them communicate their research findings with FPP in international academic meetings, as well as meetings held by the ORI scientific committee. This openly communicates research results and discusses the potential and direction of future research.Our director, Dr. Pierre Mantello is directing FPP research in Europe and has been introducing FPP as an effective food supplement for alternative healthcare in France and Italy. His efforts have made FPP accessible for many people who need it. Although FPP is made in Japan, our research results are still behind compared with the splendid research results in Europe. I would like to launch an initiative for new research projects in Japan to enhance our study.
